KMID : 0616120110420030233
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Korean Journal of Pharmacognosy 2011 Volume.42 No. 3 p.233 ~ p.239
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Quantitative Determination of Lignans from Schizandra chinensis by HPLC
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Koo Dong-Chil
Suh Won-Se Baek So-Yoon Shim Sang-Hee
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Abstract
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A reversed phase HPLC method was established for quantitative determination of lignans including schizandrin (1), gomisin A (2), deoxyschizandrin (3), gomisin N (4), and wuweizisu C (5) from Schizandra chinensis using a binary gradient of acetonitrile and water as a mobile phase with UV detection at 254nm. In result, contents of schizandrin (1), gomisin A (2), deoxyschizandrin (3), gomisin N (4), and wuweizisu C (5) in Schizandra chinensis from Moonkyung were 8.410.30, 3.010.13, 1.060.05, 7.690.30, and 1.680.06 mg/g, respectively.
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KEYWORD
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Schisandra chinensis, Quantitative analysis, Lignan, HPLC
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